+91 89850 32333info@crescoengineers.comMon–Sat · 9:00–18:00 IST
Industrial automation · Hyderabad · Since 2015

Automation for pharma, ready for audit from day one.

Cresco Engineers designs, programs, retrofits and validates control systems for lyophilizers, washing, filling, extrusion and process equipment. We are an AVEVA Registered System Integrator and a B&R Value Provider, and we produce the PLC code, SCADA, panels and IQ/OQ documents ourselves.

2015Established
5PLC platforms
Part 11Annex 11 · GAMP 5
AVEVARegistered System Integrator
Platforms we engineer on
  • Siemens
  • B&R VALUE PROVIDER
  • Allen-Bradley
  • Mitsubishi
  • Omron
  • AVEVA
Equipment we automate

We know the machines, not just the PLC

Our engineers work on sterile and oral-solid process equipment every week. We understand the process each machine runs, the failure modes, and what QA will ask about.

01LyophilizersEnd-to-end freeze dryer service: retrofits, refrigeration and SCADA upgrades, AMC
02Vial washingWashers with recipe control, pressure and flow monitoring
03Depyrogenation tunnelsHot-air sterilising tunnels: zone temperature control and HEPA monitoring
04Filling & cappingLiquid and powder filling, stoppering and sealing lines
05Hot-melt extrudersMulti-zone heating, servo feeders, torque and melt-pressure control
06Roll compactorsGranulation with roll gap, pressure and feed-screw control
07Water & utilitiesPW/WFI generation and distribution, HVAC and utility SCADA
08Leak & vacuum testingContainer closure integrity, canister leak testers, vacuum systems
AVEVA Registered System Integrator
Technology partners

AVEVA Registered System Integrator and B&R Value Provider

Cresco designs, deploys and supports AVEVA InTouch HMI and System Platform applications, and engineers B&R automation and motion systems, for regulated manufacturing. The same team writes your PLC code.

AVEVA Registered System IntegratorB&R Value Provider System Integrator
AVEVA InTouch HMIAVEVA System PlatformAVEVA HistorianB&R Automation StudioB&R motion & servoSQL Server reporting
Our integration practice
How we deliver

A delivery model your QA team will recognise

Our project flow follows the GAMP 5 lifecycle, so the documents line up with your change control and qualification steps.

  1. AssessSite survey, URS review, risk and obsolescence check
  2. SpecifyFDS, HDS/SDS, I/O lists, alarm and interlock matrices
  3. BuildPanels, PLC and SCADA developed and simulated offline
  4. FATTested at our workshop, witnessed by your team
  5. CommissionInstallation, loop checks, SAT and operator training
  6. Qualify & supportIQ/OQ execution, handover and AMC
Recent & ongoing work

What we are working on

A selection of current and recent work. Client names are kept confidential on project details; references are available on request.

Lyophilisation · End-to-end

Freeze dryer services: retrofits to AMC

End-to-end freeze dryer support: retrofits, control panel upgrades, Windows, PLC and SCADA upgrades, mechanical upgrades, TXV to EEV/ETV conversions, compressor upgrades, SQL Server/SSRS cycle reports and AMC.

RetrofitPLC / SCADAEEV / ETVCompressorsAMC
Injectables · Utilities

Water system SCADA modification

Modified the SCADA application for a purified-water and distribution system at an injectables facility, including screens, alarms, reporting and change-control documentation.

SCADAWater systemGMP change control
Oral solids · Process equipment

Hot-melt extruder controls & PROFINET servo integration

Full documentation suite and PROFINET integration of servo drives with a Siemens PLC for a pharmaceutical hot-melt extruder, covering alarms, interlocks and qualification documents.

S7-1500Stober SDS5000PROFINETIQ/OQ
Oral solids · Granulation

Roll compactor IPC & SCADA upgrade

Replacing an ageing IPC/SCADA on a roll compactor with a supported platform built on AVEVA InTouch HMI, with recipes, audit trail and reporting.

AVEVA InTouchIPC upgrade21 CFR Part 11
Formulations · Field service

PLC upgrades & field service

PLC upgrades, breakdown support and field service reporting for formulation plants of a leading Indian pharmaceutical company.

Siemens S7DrivesField service
Vaccines · Automation

Automation & validation for a vaccine maker

Automation, validation documents and proposals for process equipment at a major Indian vaccine and biologicals manufacturer.

ValidationProcess automationBiologics
Compliance outlook 2026

Regulations are changing, and so is how we validate

Data integrity and computerised-system expectations are tightening. We track the guidance so your systems meet current expectations when they are commissioned.

US FDA · Final guidance, 2025

Computer Software Assurance

The FDA’s CSA guidance moves effort from scripted documentation to risk-based testing of the functions that affect product quality. We size our OQ effort the same way.

EU GMP · Draft revision

Annex 11 update

The draft revision of EU GMP Annex 11 places more weight on audit-trail review, identity and access management, cybersecurity and supplier oversight. A new Annex 22 on AI was drafted alongside it. Our designs already cover these areas.

Industry 4.0 · Pharma 4.0

Connected, secured OT

OPC UA, historians and IEC 62443-style segmentation let you use plant data for reports and dashboards without exposing the control network.

21 CFR Part 11EU GMP Annex 11GAMP 5 (2nd Ed.)FDA CSAALCOA+ISA-88ISA-101IEC 62443GS1
Trusted by

Clients across pharma, biotech and healthcare

From global generic manufacturers to vaccine makers and hospitals, our clients return to us for upgrades, AMCs and new projects.

Dr. Reddy's Laboratories
Fresenius Kabi
Hetero
Biological E. Limited
Eugia Pharma
Sun Pharma
Tofflon
Onesource
Aurobindo
Indian Immunologicals Limited
KIMS Hospitals
Shilpa
Cronus Pharma
Stanex Drugs & Chemicals
Radix
Ciron Drugs & Pharmaceuticals
Ichor Biologics
VJ Biosciences
Sovereign
Schematic Technology
Euroteck Environmental
Aspiro Pharma
Anthea Pharma
Sanzyme
Sakar Healthcare
Pharma Pack
Nuclear Fuel Complex
Matrix Pharma Corp
Schenergix
Maiva Pharma

Planning an upgrade, a new line or a qualification?

Tell us about the machine, the process and the deadline. An engineer, not a salesperson, will reply within one working day.